Multispec+ system components
Multispec+ analytical components
Multispec+ from Microdom is a patented coupled Fourier-transform infrared / ultraviolet visible spectrometer. The system components include:
- iS10 FTIR spectrometer from Thermo Fischer Scientific. Transmittance flow-cell with a path length of 20 μm. Nicolet EZ Omnic FTIR software included
- Diode array UV/Visible spectrometer, range 190 - 900 nm, equipped with a 0.2 mm flow-cell
- Dedicated autosampler, Microprep, for the safe transfer of samples from sealed vials to the measure cells
- Carrousel with 40 vial positions. Automatic sample identification with onboard barcode reader. Sample dilution capability
Multispec+ software analysis
Multispec+ Analysis is the application software for the routine operation of the system and the configuration of the analytical protocols. Key features include:
- Access control with login and password
- Selection and adjustment of quantification calibrations and identification libraries
- Standardisation of the measure flow cells
- Routine analysis
- Reanalysis function
- Result printing and export (text, Microsoft Access or Excel format)
Multispec+ identification libraries
The identification of molecules and diluents is based on a spectral library included in the software package. The library includes more than 50 molecules diluted with either NaCl or glucose (cytotoxics, monoclonal antibodies). It can be easily edited and complemented with new spectra. Specific libraries dedicated to other classes of therapeutic classes of molecules can be developed by users on site.
Multispec+ quantification
- Adjustment of calibration parameters (slope and bias)
- Development and edition of identification libraries
- Development of quantification calibrations in MLR (Multiple
Linear Regression) or PLS (Partial Least Squares) mode - Calibration development toolbox for the selection of the optimal spectral band, cross-validation, number of factors, correlation and variance
- Display of spectra in graphic mode
Multispec+ quantification calibrations
The concentration assessment is performed by quantification calibrations delivered with the software package. These calibrations cover the great majority of the usually prescribed molecules.
Multispec+ worklist editor
This utility is designed to enable the separation of the sample identification step from the actual processing step. It can be installed on any PC accessible by the command PC of Multispec+ via the pharmacy LAN. The operator can check at all time the progress of the analysis process.
Multispec+ analysis control utility
This utility is an Excel-based spreadsheet designed to confront the prescription data, uploaded from the pharmacy information and system with the analytical results worked out by Multispec+.
The Multispec+analyzer from Microdom offers absolute and cost-effective qualitative & quantitative control of high-risk medications compounded in the hospital pharmacy workflow, seamlessly, rapidly, consistently.
